电子邮件:[email protected]
通讯地址:上海市东川路800号上海交通大学化学C楼609
个人主页: //sites.google.com/view/denglab/home
2009-2014,四川大学,工学博士,导师:褚良银教授
2005-2009,四川大学,工学学士,导师:褚良银教授
2019-至今,上海交通大学,长聘教轨副教授,博士生导师
2017-2019,美国哈佛大学,博士后,合作导师:Prof. George M. Whitesides
2014-2017,荷兰内梅亨大学,博士后/玛丽居里学者,合作导师:Prof. Wilhelm T.S. Huck
本课题组主要从事人工细胞、活性软物质、微纳米机器人、液-液相分离和微流控技术相关的基础研究和技术开发,具体包括:
1)人工细胞和原始细胞(Artificial cells & Protocells)
2)活性物质/软物质 (Active matter & Soft matter)
3)液液相分离(ATPS、Coacervates、DNA液滴等)
4)液滴微流控技术
5) 微纳米机器人
6)单细胞基因测序建库技术
主持国家自然科学基金青年项目(已结题)、面上项目(2)、国家青年千人项目(已结题)、上海市面上项目、四川省面上项目、四川省天府峨眉计划、上交绍兴研究院开放基金(已结题),共同主持上交医工交叉青年(已结题)、重点项目和若干横向课题等。
Full publication list:
//scholar.google.com/citations?user=6i5ARiQAAAAJ&hl=en
Selected Publicaitons:
†Co-first author; *Corresponding author
22) Jia-Yao Wang, Ming-Di Gao, Chao-Yang Guan, Jin-Ying Qi, Nan-Nan Deng.* Ultraviolet and Visible Light-Responsive RNA Photofluids. Angewandte Chemie International Edition, 2025, e202515264.
//doi.org/10.1002/anie.202515264

21) Jin-Ying Qi†, Qi-Hong Zhao†, Nan-Nan Deng.* A Photo-active Synthetic Cell. CCS Chemistry, 2025,
//doi.org/10.31635/ccschem.025.202506237

20) Zhen-Hong Luo, Xuan-Yan He, Nan-Nan Deng.* Monodisperse Giant Unilamellar Niosomes as Minimal Synthetic Cells. Journal of the American Chemical Society, 2025, 147, 27081−27088.
//doi.org/10.1021/jacs.5c09950

19) Muhammad Umar Farooq, Charles H. Lawrie, Nan-Nan Deng.* Solving Mazes of Organelle-targeted Therapies with DNA Nanomachines. Advanced Materials, 2025, 37, 250804737, 2508047. (Review)
//doi.org/10.1002/adma.202508047

18) Zhenhua Li,+ Qing Liu,+ Han Ding, Zhuojun Meng, Qi-Hong Zhao, Nan-Nan Deng,* Lifei Zheng.* Static and transient vacuolation in protein-based coacervates induced by charged amino acids. Nature Communications, 2025, 16, 5837.
//doi.org/10.1038/s41467-025-61340-w

17) Qi-Hong Zhao, Jin-Ying Qi, Nan-Nan Deng.* DNA photofluids show life-like motion. Nature Materials, 2025, 24 (6), 935−944.
//doi.org/10.1038/s41563-025-02202-0. (free access: //rdcu.be/eg1x9)

News & Views:
Brigitta Dúzs,* Andreas Walther.* DNA droplets shuffle in the spotlight. Nature Materials, 2025, 24, 816−817.
//doi.org/10.1038/s41563-025-02226-6
16) Dong‐Yu Li, Nan‐Nan Deng.* Transient Structural Coloration During Dewetting Transition of Water‐In‐Oil‐In‐Water Droplets. Small, 2025, 2503654.
//doi.org/10.1002/smll.202503654

15) Yao-Yao Su, Da-Wei Pan,* Tao-Xian Zhang, Rui Xie, Xiao-Jie Ju, Zhuang Liu, Nan-Nan Deng,* Wei Wang,* Liang-Yin Chu. Wetting-induced Interfacial Instability: A Mechanism for Droplet Emission at Air-liquid Interfaces. Science Advances, 2025, 11(12), ads1065.
//www.science.org/doi/10.1126/sciadv.ads1065

14) Jia-Qi Tian, Nan-Nan Deng.* Dynamic satellite-parent liposome networks for quantitative microreactions. Chemical Science, 2024,
15, 19619−19625.

13) Jia-Qi Tian, Mu-Yueh Chang, Chen Chen, Zhen-Hong Luo, Wilhelm T. S. Huck, Nan-Nan Deng.* Interfacial Energy-mediated Bulk Transport across Artificial Cell Membranes. Nature Chemical Engineering, 2024, 1 (7), 450–461.
//www.nature.com/articles/s44286-024-00088-4 (Free PDF access link: rdcu.be/dMKyA)

News & views:
Atul N. Parikh.* Controlling transport across artificial cell membranes. Nature Chemical Engineering, 2024, 1 (7), 447–449.
//www.nature.com/articles/s44286-024-00091-9
12) Zhen-Hong Luo†, Chen Chen†, Qi-Hong Zhao, Nan-Nan Deng.* Functional Metal-phenolic Cortical Cytoskeleton for Artificial Cells. Science Advances, 2024, 10, eadj4047.
//www.science.org/doi/10.1126/sciadv.adj4047

11) Dong-Yu Li, Wei Wang, Liang-Yin Chu, and Nan-Nan Deng.* Tunable Structural Coloration in Eccentric Water-in-Oil-in-Water Droplets. Nano Letters, 2023, 23, 9657−9663. (Supplementary Cover)
//doi.org/10.1021/acs.nanolett.3c02119.

10) Mu-Yueh Chang, Hirotaka Ariyama, Wilhelm T. S. Huck,* Nan-Nan Deng.* Division in synthetic cells. Chemical Society Review, 2023, 52, 3307−3325. (Review)

9) Qi-Hong Zhao,+ Fang-Hao Cao,+ Zhen-Hong Luo, Wilhelm TS Huck, Nan-Nan Deng.* Photoswitchable Molecular Communication between Programmable DNA‐based Artificial Membraneless Organelles. Angewandte Chemie International Edition, 2022, 61, e202117500.
//doi.org/10.1002/anie.202117500

Before SJTU:
8) Nan-Nan Deng,* Mahesh Vibhute, Lifei Zheng, Hui Zhao, Maaruthy Yelleswarapu, Wilhelm TS Huck.* Macromolecularly crowded protocells from reversibly shrinking monodisperse liposomes. Journal of the American Chemical Society, 2018, 140, 7399−7402.
//doi.org/10.1021/jacs.8b03123

7) Nan-Nan Deng,* Wilhelm T. S. Huck.* Microfluidic formation of monodisperse coacervate organelles in liposomes. Angewandte Chemie International Edition, 2017, 56, 9736−9740.
//doi.org/10.1002/anie.201703145

6) Nan-Nan Deng, Maaruthy Yelleswarapu, Life Zheng, Wilhelm T. S. Huck.* Microfluidic assembly of monodisperse vesosomes as artificial cell models. Journal of the American Chemical Society, 2017, 139, 587−590. (Front Cover, highlighted by JACS Spotlight)
//doi.org/10.1021/jacs.6b10977

5) Nan-Nan Deng, Maaruthy Yelleswarapu, Wilhelm T. S. Huck.* Monodisperse uni- and multi-compartment liposomes. Journal of the American Chemical Society, 2016, 138, 7584−7591.
//doi.org/10.1021/jacs.6b02107

4) Nan-Nan Deng, Wei Wang, Xiao-Jie Ju, Rui Xie, Liang-Yin Chu.* Spontaneous transfer of droplets across microfluidic laminar interfaces. Lab on a Chip, 2016, 16, 4326−4332. (Front Cover)
//pubs.rsc.org/en/content/articlelanding/2016/lc/c6lc01022a

3) Deng N.N., Wang W., Ju X.J., Xie R., Weitz D.A., Chu L.Y. Wetting-induced formation of controllable monodisperse multiple emulsions in microfluidics. Lab on a Chip, 2013, 13, 4047−4052. (Back Cover)
//pubs.rsc.org/en/content/articlelanding/2013/lc/c3lc50638j
2) Deng N.N., Sun S.X., Wang W., Ju X.J., Xie R., Chu L.Y. A novel surgery-like strategy for droplet coalescence in microchannels. Lab on a Chip, 2013, 13, 3653−3657.
//pubs.rsc.org/en/content/articlelanding/2013/lc/c3lc50533b
1) Deng N.N., Meng Z.J., Xie R., Ju X.J., Mou C.L., Wang W., Chu L.Y. Simple and cheap microfluidic devices for preparation of monodisperse emulsions. Lab on a Chip, 2011, 11, 3963−3969. (Back Cover)
//pubs.rsc.org/en/content/articlelanding/2011/lc/c1lc20629j
Reviewers for:
Nature Nanotechnology, Nature Chemistry, Nature Chemical Engineering, JACS, Nature Communications, Angew. Chem., Chem, ACS Nano, Chem. Sci., Chem. Comm., Lab on a Chip, AFM, Small, AIChE Journal, etc.

2021 天府峨眉计划
2021 全球华人化工学会 “未来化工学者”
2019 国家高层次海外人才计划
2015-2017 欧盟玛丽居里学者
2014 四川大学优秀博士毕业生
2013 博士研究生国家奖学金
2013 赢创奖学金
2012 宝钢奖学金
本科生:《化工原理基础》(致远学院),《化工原理基础》(易游娱乐官网 )
研究生:《绿色化工》
前沿课:《化学工程与技术前沿专题》、《化学生物学》
2024 上海交通大学优秀班主任
2024 上海交通大学青教赛 二等奖
招收2026年春季或秋季入学博士生(申请-考核)
具体要求:
1.具有高分子、超分子组装或多酶催化等相关背景,已经/即将获得硕士学位;
2.有高水平论文发表经历(审稿中亦可);
3.踏实勤奋、有学术志向。
联系方式: [email protected]
课题组常年招收博士后,欢迎邮件联系;
欢迎有志于科学研究的本科生进入实验室进行科研训练。